Lyon IARC Polyomavirus Displays Transforming Activities in Primary Human Cells-Reference-Cited by-同舟云学术

Lyon IARC Polyomavirus Displays Transforming Activities in Primary Human Cells

Published:2022-07-27 Issue:14 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Venuti Assunta¹,Romero-Medina Maria Carmen¹,Melita Giusi¹,Ceraolo Maria Grazia¹,Brancaccio Rosario Nicola¹,Sirand Cecilia¹,Taverniti Valerio¹,Steenbergen Renske²,Gheit Tarik¹^ORCID,Tommasino Massimo³^ORCID

Affiliation:

1. International Agency for Research on Cancer (IARC), World Health Organization, Lyon Cedex, France

2. VU University Medical Center Amsterdam, Department of Pathology, Amsterdam, The Netherlands

3. IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy

Abstract

Lyon IARC PyV is a recently discovered polyomavirus that shows some structural similarities to well-established animal and human oncogenic PyVs, such as raccoon PyV and Merkel cell PyV, respectively. Here, we show the capability of LIPyV to efficiently promote cellular transformation of primary human cells, suggesting a possible oncogenic role of this virus in domestic animals and/or humans.

Funder

Fondation ARC pour la Recherche sur le Cancer

Institut National de la Santé et de la Recherche Médicale

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.02061-21

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