Arginine or Nitrate Enhances Antibiotic Susceptibility of Pseudomonas aeruginosa in Biofilms-Reference-Cited by-同舟云学术

Arginine or Nitrate Enhances Antibiotic Susceptibility of Pseudomonas aeruginosa in Biofilms

Published:2006-01 Issue:1 Volume:50 Page:382-384
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Borriello Giorgia¹,Richards Lee¹,Ehrlich Garth D.²,Stewart Philip S.¹

Affiliation:

1. Center for Biofilm Engineering and Department of Chemical Engineering, Montana State University—Bozeman, Bozeman, Montana 59717-3980

2. Center for Genomic Sciences, Allegheny Singer Research Institute, 320 E. North Ave., Pittsburgh, Pennsylvania 15212

Abstract

ABSTRACT Arginine enhanced the killing of Pseudomonas aeruginosa by ciprofloxacin and tobramycin under anaerobic, but not aerobic, growth conditions. Arginine or nitrate also enhanced the killing by these antibiotics in mature biofilms, reducing viable cell counts by a factor of 10 to 100 beyond that achieved by antibiotics alone.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.50.1.382-384.2006

Reference17 articles.

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