Virus-Like Vesicles Based on Semliki Forest Virus-Containing Rabies Virus Glycoprotein Make a Safe and Efficacious Rabies Vaccine Candidate in a Mouse Model-Reference-Cited by-同舟云学术

Virus-Like Vesicles Based on Semliki Forest Virus-Containing Rabies Virus Glycoprotein Make a Safe and Efficacious Rabies Vaccine Candidate in a Mouse Model

Published:2021-09-27 Issue:20 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Zhang Chengguang¹²³,Tian Yuling¹²³,Chen Chen¹²³,Wang Zongmei¹²³,Pei Jie¹²³,Lin Chuhan¹²³,Zhou Ming¹²³,Fu Zhen F.¹²³,Zhao Ling¹²³^ORCID

Affiliation:

1. State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China

2. Key Laboratory of Preventive Veterinary Medicine of Hubei Province, Huazhong Agricultural University, Wuhan, China

3. College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China

Abstract

VLVs have been shown to represent a more versatile and superior vaccine platform. In previous studies, VLVs containing the Semliki Forest virus replicase (SFV nsP1 to nsP4) and rabies virus glycoprotein (RABV-G) grew to relatively low titers in cells.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00790-21

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