A modified recombinant adenovirus vector containing dual rabies virus G expression cassettes confers robust and long-lasting humoral immunity in mice, cats, and dogs

Author:

Zhang Yuan123,Fang Lingying123,Wang Zongmei123,Zhang Chengguang123,Zhao Jianqing123,Daemi Hakimeh Baghaei123,Zhang Mai123,Yuan Liwen123,Han Xiaohu123,Li Linfeng123,Fu Zhen F.123ORCID,Zhou Ming23,Zhao Ling1423ORCID

Affiliation:

1. National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, People’s Republic of China

2. Frontiers Science Center for Animal Breeding and Sustainable Production, Wuhan, People’s Republic of China

3. Key Laboratory of Preventive Veterinary Medicine of Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, People’s Republic of China

4. Hubei Hongshan Laboratory, Wuhan, People’s Republic of China

Funder

National Key Research and Development Program of China

Fundamental Research Funds for the Central Universities

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

Reference60 articles.

1. Estimating the global burden of endemic canine rabies;Hampson K;PLoS Negl Trop Dis,2015

2. GBD 2010: design, definitions, and metrics

3. World Health Organization. WHO expert consultation on rabies: third report [Internet]. Geneva: World Health Organization; 2018 [cited 2023 Aug 15]. Available from: https://apps.who.int/iris/handle/10665/272364.

4. Rabies: 100 per cent fatal, 100 per cent preventable

5. Advances in rabies prophylaxis and treatment with emphasis on immunoresponse mechanisms

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