Virus inactivation by copper or iron ions alone and in the presence of peroxide

Author:

Sagripanti J L1,Routson L B1,Lytle C D1

Affiliation:

1. Division of Life Sciences, Food and Drug Administration, Rockville, Maryland 20852.

Abstract

Cupric and ferric ions were able to inactivate five enveloped or nonenveloped, single- or double-stranded DNA or RNA viruses. The virucidal effect of these metals was enhanced by the addition of peroxide, particularly for copper(II). Under the conditions of our test, mixtures of copper(II) ions and peroxide were more efficient than glutaraldehyde in inactivating phi X174, T7, phi 6, Junin, and herpes simplex viruses. The substances described here should be able to inactivate most, if not all, viruses that have been found contaminating medical devices.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference12 articles.

1. Method for improving accuracy of virus titration: standardization of plaque assay for Junin virus;Bushar G.;J. Virol. Methods,1990

2. Respiratory physicians: attitudes to invasive procedures in high risk, HIV positive, and AIDS patients;Church S.E.;Thorax,1988

3. Favero M. S. N. J. Petersen and W. W. Bond. 1986. Transmission and control of laboratory-acquired hepatitis infection p. 49-58. In B. M. Miller D. H. M. Groschel J. H. Richardson D. Vesley J. R. Songer R. D. Housewright and W. E. Barkley (ed.) Laboratory safety: principles and practices. American Society for Microbiology Washington D.C.

4. AIDS, aprons, and elbow grease: preventing the nosocomial spread of immunodeficiency virus and associated organisms;Hanson P. J. V.;Thorax,1989

5. Host-cell reactivation in mammalian cells. I. Survival of ultraviolet-irradiated herpes virus in different celllines;Lytle C. D.;Int. J. Radiat. Biol.,1971

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