A new Cu(<scp>ii</scp>) complex derived from the reaction between tris(2-aminoethyl)amine and Cu(<scp>i</scp>)-activated acetonitrile with potent anticancer activity against some cell lines and high affinity for the essential proteins of SARS-CoV-2-Reference-Cited by-同舟云学术

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A new Cu(ii) complex derived from the reaction between tris(2-aminoethyl)amine and Cu(i)-activated acetonitrile with potent anticancer activity against some cell lines and high affinity for the essential proteins of SARS-CoV-2

Published:2024 Issue:5 Volume:48 Page:2251-2260
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Hajibabaei Farshid¹,Salehzadeh Sadegh¹^ORCID,Derakhshandeh Katayoun²³,Gable Robert William⁴^ORCID

Affiliation:

1. Faculty of Chemistry and Petroleum of Sciences, Bu-Ali Sina University, Hamedan, Iran

2. Department of Pharmaceutics, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran

3. Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran

4. School of Chemistry, University of Melbourne, Victoria 3010, Australia

Abstract

The new Cu(ii) complex (CuL) can target both the DNA and SARS-CoV-2 protein.

Funder

Bu Ali Sina University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D3NJ04142E

Reference56 articles.

1. Application of neutral amidines and guanidines in coordination chemistry

2. Al and Zn phenoxy-amidine complexes for lactide ROP catalysis

3. Construction of Double-Stranded Metallosupramolecular Polymers with a Controlled Helicity by Combination of Salt Bridges and Metal Coordination

4. Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency

5. Arginine mimetics

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