Microbial Interactions in a Vitamin C Industrial Fermentation System: Novel Insights and Perspectives

Author:

Zhang Qian1,Lyu Shuxia1ORCID

Affiliation:

1. College of Bioscience and Biotechnology, Shenyang Agricultural University, Shenyang, Liaoning, China

Abstract

In industrial production, the precursor of l -ascorbic acid (L-AA, also referred to as vitamin C), 2-keto- l -gulonic acid (2-KLG), is mainly produced using a classic two-step fermentation process performed by Gluconobacter oxydans , Bacillus megaterium , and Ketogulonicigenium vulgare . In the second step of the two-step fermentation process, the microbial consortium of K. vulgare and B. megaterium is used to achieve 2-KLG production. K. vulgare can transform l -sorbose to 2-KLG, but the yield of 2-KLG is much lower in the monoculture than in the coculture fermentation system.

Funder

National Science Fundation of China

Liaoning Province Science Research Fund

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference48 articles.

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4. Transcriptome Analysis of Gluconobacter oxydans WSH-003 Exposed to Elevated 2-Keto-L-Gulonic Acid Reveals the Responses to Osmotic and Oxidative Stress

5. Studies on the production of vitamin C precursor-2-keto-l-gulonic acid from l-sorbose by fermentation. I. Isolation, screening and identification of 2-keto-l-gulonic acid producing bacteria;Yin G;Acta Microbiol Sin,1980

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