Affiliation:
1. Institute of Microbiology and Biomedical Sciences, Polytechnic University of Marche, 60131 Ancona, Italy
Abstract
ABSTRACT
Four isogenic derivatives with stably increased glycopeptide MICs (all become resistant to teicoplanin) were obtained from four glycopeptide-susceptible clinical isolates of
Staphylococcus haemolyticus
. All strains were extensively analyzed and compared for a number of distinctive features. In particular, the results provided insights into the puzzling issue of antistaphylococcal interactions between glycopeptides and β-lactams, especially the paradox of double zones around β-lactam disks and the relationships between autolysis rate and type of interaction.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
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