Mechanistic Basis for Understanding the Dual Activities of the Bifunctional Azotobacter vinelandii Mannuronan C-5-Epimerase and Alginate Lyase AlgE7

Author:

Gaardløs Margrethe1ORCID,Heggeset Tonje Marita Bjerkan12ORCID,Tøndervik Anne2,Tezé David34ORCID,Svensson Birte3ORCID,Ertesvåg Helga1ORCID,Sletta Håvard2,Aachmann Finn Lillelund1ORCID

Affiliation:

1. Norwegian Biopolymer Laboratory (NOBIPOL), Department of Biotechnology and Food Science, NTNU Norwegian University of Science and Technology, Trondheim, Norway

2. Department of Biotechnology and Nanomedicine, SINTEF Industry, Trondheim, Norway

3. Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark

4. Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, Denmark

Abstract

Postharvest valorization and upgrading of algal constituents are promising strategies in the development of a sustainable bioeconomy based on algal biomass. In this respect, alginate epimerases and lyases are valuable enzymes for tailoring the functional properties of alginate, a polysaccharide extracted from brown seaweed with numerous applications in food, medicine, and material industries.

Funder

The Research Council of Norway

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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