Staphylococcus aureus Biofilm-Conditioned Medium Impairs Macrophage-Mediated Antibiofilm Immune Response by Upregulating KLF2 Expression-Reference-Cited by-同舟云学术

Staphylococcus aureus Biofilm-Conditioned Medium Impairs Macrophage-Mediated Antibiofilm Immune Response by Upregulating KLF2 Expression

Published:2019-04 Issue:4 Volume:87 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Alboslemy Talib¹²,Yu Bing³,Rogers Tara³,Kim Min-Ho¹³

Affiliation:

1. School of Biomedical Sciences, Kent State University, Kent, Ohio, USA

2. Department of Biology, College of Sciences, University of Basrah, Basrah, Iraq

3. Department of Biological Sciences, Kent State University, Kent, Ohio, USA

Abstract

Staphylococcus aureus infections associated with the formation of biofilms on medical implants or host tissue play a critical role in the persistence of chronic infections. One critical mechanism of biofilm infection that leads to persistent infection lies in the capacity of biofilms to evade the macrophage-mediated innate immune response.

Funder

HHS | NIH | National Institute of Nursing Research

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00643-18

Reference35 articles.

1. The Burden of Staphylococcus aureus Infections on Hospitals in the United States

2. Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

3. Staphylococcus aureus biofilms: recent developments in biofilm dispersal