Effects of Rifamycin Derivatives, Alone and in Combination with Amphotericin B, Against Histoplasma capsulatum-Reference-Cited by-同舟云学术

Effects of Rifamycin Derivatives, Alone and in Combination with Amphotericin B, Against Histoplasma capsulatum

Published:1974-01 Issue:1 Volume:5 Page:16-18
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Kobayashi George S.¹,Cheung Sze-Schuen C.¹,Schlessinger David¹,Medoff Gerald¹

Affiliation:

1. Divisions of Dermatology and Infectious Diseases, Departments of Medicine and Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110

Abstract

Several derivatives of rifamycin SV inhibited ribonucleic acid synthesis and decreased the viability of Histoplasma capsulatum . Both of these effects were enhanced by low concentrations of amphotericin B. The relative potency of the different rifamycin derivatives against H. capsulatum , when used in combination with amphotericin B or alone, was the same as that reported for the inhibition of the reverse transcriptase of ribonucleic acid tumor viruses.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.5.1.16

Reference8 articles.

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4. Potentiation of the antifungal effects of antibiotics by amphoterecin B;Kwan C. N.;Antimicrob. Ag. Chemother.,1972

5. Potentiation of rifampicin and 5-fluorocytosine as antifungal antibiotics by amphotericin B;Medoff G.;Proc. Nat. Acad. Sci. U.S.A.,1972

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