New Automated Method for Determining Postantifungal Effect of Amphotericin B against Candida Species: Effects of Concentration, Exposure Time, and Area under the Curve-Reference-Cited by-同舟云学术

New Automated Method for Determining Postantifungal Effect of Amphotericin B against Candida Species: Effects of Concentration, Exposure Time, and Area under the Curve

Published:2002-12 Issue:12 Volume:46 Page:4016-4018
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Chryssanthou Erja¹,Cars Otto²,Sjölin Jan²

Affiliation:

1. Department of Clinical Microbiology, Karolinska Hospital, Stockholm

2. Antibiotic Research Unit, Section of Infectious Diseases, Department of Medical Sciences, University Hospital, Uppsala, Sweden

Abstract

ABSTRACT The postantifungal effect (PAFE) of amphotericin B was determined with a BacT/Alert automated system, which is based on the colorimetric detection of CO 2 . The levels of accuracy and precision of the automated method were high. Longer PAFEs were obtained for Candida albicans ( P < 0.001), C. glabrata ( P < 0.01), and C. krusei ( P < 0.01) at increasing amphotericin B concentrations and exposure times.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.46.12.4016-4018.2002

Reference9 articles.

1. Bindschadler, D. D., and J. E. Bennett. 1968. A pharmacologic guide to the clinical use of amphotericin B. J. Infect. Dis.120:427-436.

2. Craig W. A. and S. Gudmundsson. 1996. The postantibiotic effect p. 296-329. In V. Lorian (ed.) Antibiotics in laboratory medicine 4th ed. Williams and Wilkins Baltimore Md.

3. Ellepola, A. N., and L. P. Samaranayake. 1998. The postantifungal effect (PAFE) of antimycotics on oral C. albicans isolates and its impact on candidal adhesion. Oral Dis.4:260-267.

4. Ericsson, U., B. Seifert, and A. Schaffner. 2001. Comparison of effects of amphotericin B deoxycholate infused over 4 or 24 hours: randomised controlled trial. Br. Med. J.322:579-582.

5. Antifungal pharmacodynamic characteristics of fluconazole and amphotericin B tested against Candida albicans

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