Temporin A Soaking in Combination with Intraperitoneal Linezolid Prevents Vascular Graft Infection in a Subcutaneous Rat Pouch Model of Infection with Staphylococcus epidermidis with Intermediate Resistance to Glycopeptides-Reference-Cited by-同舟云学术

Temporin A Soaking in Combination with Intraperitoneal Linezolid Prevents Vascular Graft Infection in a Subcutaneous Rat Pouch Model of Infection with Staphylococcus epidermidis with Intermediate Resistance to Glycopeptides

Published:2004-08 Issue:8 Volume:48 Page:3162-3164
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Giacometti Andrea¹,Cirioni Oscar¹,Ghiselli Roberto²,Orlando Fiorenza³,D'Amato Giuseppina¹,Kamysz Wojciech⁴,Mocchegiani Federico²,Sisti Valerio²,Silvestri Carmela¹,Łukasiak Jerzy⁴,Rocchi Marco⁵,Saba Vittorio²,Scalise Giorgio¹

Affiliation:

1. Institute of Infectious Diseases and Public Health, Università Politecnica delle Marche

2. Department of General Surgery, I.N.R.C.A. I.R.C.C.S., Università Politecnica delle Marche

3. Biotechnology Centre, Research Department, I.N.R.C.A. I.R.C.C.S., Ancona

4. Faculty of Pharmacy, Medical University of Gdańsk, Gdańsk, Poland

5. Institute of Biomathematics, Faculty of Pharmacy, University of Urbino, Urbino, Italy

Abstract

ABSTRACT The efficacy of linezolid and temporin A in the prevention of prosthetic graft infection due to methicillin-resistant Staphylococcus epidermidis with intermediate resistance to glycopeptides was investigated in a subcutaneous rat pouch model. Linezolid and temporin A, alone or combined, greatly reduced the bacterial numbers compared to the effect with control drugs.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.48.8.3162-3164.2004

Reference19 articles.

1. Balaban, N., A. Giacometti, O. Cirioni, R. Ghiselli, F. Mocchegiani, Y. Gov, M. S. Del Prete, C. Viticchi, V. Saba, G. Scalise, and G. Dell'Acqua. 2003. In vivo prevention of Staphylococcus epidermidis biofilm by RIP, a quorum sensing inhibitor. J. Infect. Dis.187:625-630.

2. Bergamini, T. M., J. C. Peyton, and W. G. Cheadle. 1992. Prophylactic antibiotics prevent bacterial biofilm graft infection. J. Surg. Res.52:101-105.

3. Cirioni, O., A. Giacometti, R. Ghiselli, G. Dell'Acqua, Y. Gov, W. Kamysz, J. Łukasiak, F. Mocchegiani, F. Orlando, G. D'Amato, N. Balaban, V. Saba, and G. Scalise. 2003. Prophylactic efficacy of topical temporin A and RNAIII-inhibiting peptide in a subcutaneous rat pouch model of graft infection attributable to staphylococci with intermediate resistance to glycopeptides. Circulation108:767-771.

4. Bacterial Biofilms: A Common Cause of Persistent Infections

5. Efficacy of Linezolid in Treatment of Experimental Endocarditis Caused by Methicillin-Resistant Staphylococcus aureus

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