The Fused Methionine Sulfoxide Reductase MsrAB Promotes Oxidative Stress Defense and Bacterial Virulence in Fusobacterium nucleatum-Reference-Cited by-同舟云学术

The Fused Methionine Sulfoxide Reductase MsrAB Promotes Oxidative Stress Defense and Bacterial Virulence in Fusobacterium nucleatum

Published:2022-06-28 Issue:3 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Scheible Matthew¹,Nguyen Cuong T.²,Luong Truc Thanh¹,Lee Ju Huck²³,Chen Yi-Wei¹,Chang Chungyu¹,Wittchen Manuel⁴,Camacho Martha I.¹,Tiner Bethany L.²,Wu Chenggang²,Tauch Andreas⁴,Das Asis⁵,Ton-That Hung¹⁶^ORCID

Affiliation:

1. Division of Oral Biology and Medicine, School of Dentistry, University of California, Los Angeles, California, USA

2. Department of Microbiology & Molecular Genetics, University of Texas McGovern Medical School, Houston, Texas, USA

3. Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea

4. Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany

5. Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, Connecticut, USA

6. Molecular Biology Institute, University of California, Los Angeles, Los Angeles, California, USA

Abstract

F. nucleatum colonizes various human tissues, including oral cavity, placenta, and colon. How this obligate anaerobe withstands oxidative stress in host immune cells has not been described.

Funder

HHS | NIH | National Institute of Dental and Craniofacial Research

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.03022-21

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