Can Dietary Fatty Acids Affect the COVID-19 Infection Outcome in Vulnerable Populations?

Author:

Onishi J. C.1ORCID,Häggblom M. M.12ORCID,Shapses S. A.324ORCID

Affiliation:

1. Department of Biochemistry and Microbiology, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA

2. New Jersey Institute for Food, Nutrition & Health, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA

3. Department of Nutritional Sciences, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA

4. Department of Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA

Abstract

There is high mortality in coronavirus disease 2019 (COVID-19)-infected individuals with chronic inflammatory diseases, like obesity, diabetes, and hypertension. A cytokine storm in some patients after infection contributes to this mortality. In addition to lungs, the intestine is targeted during COVID-19 infection. The intestinal membrane serves as a barrier to prevent leakage of microorganisms and their products into the bloodstream; however, dietary fats can affect the gut microbiome and may increase intestinal permeability.

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Reference44 articles.

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