Concentration of ciprofloxacin in human prostatic tissue after oral administration-Reference-Cited by-同舟云学术

Concentration of ciprofloxacin in human prostatic tissue after oral administration

Published:1986-07 Issue:1 Volume:30 Page:88-89
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Dan M,Golomb J,Gorea A,Braf Z,Berger S A

Abstract

Concomitant concentrations of ciprofloxacin in serum, urine, and prostatic tissue were determined in 15 patients after single oral doses of 750 mg. Levels in tissue ranged from 0.6 to 4.18 micrograms/g, and therapeutic concentrations were demonstrable for up to 9 h after administration. The mean ratio of tissue to serum concentration was 0.93 +/- 0.08 (standard error).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.30.1.88

Reference9 articles.

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4. Pharmacokinetics and tissue penetration of ciprofloxacin;Crump B.;Antimicrob. Agents Chemother.,1983

5. Diffusion of ciprofloxacin into prostatic fluid;Dalhoff A.;Eur. J. Clin. Microbiol.,1984

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