Activation of the <i>Plasmodium</i> Egress Effector Subtilisin-Like Protease 1 Is Mediated by Plasmepsin X Destruction of the Prodomain-Reference-Cited by-同舟云学术

Activation of the Plasmodium Egress Effector Subtilisin-Like Protease 1 Is Mediated by Plasmepsin X Destruction of the Prodomain

Published:2023-04-25 Issue:2 Volume:14 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Mukherjee Sumit¹,Nasamu Armiyaw S.¹,Rubiano Kelly C.¹,Goldberg Daniel E.¹^ORCID

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, and Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA

Abstract

Malaria parasites replicate inside a parasitophorous vacuole within the host red blood cells. The exit of mature progeny from the infected host cells is essential for further dissemination.

Funder

American Heart Association

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00673-23

Reference37 articles.

1. World Health Organization. 2020. WHO world malaria report 2020. World Health Organization, Geneva, Switzerland.

2. Rounding precedes rupture and breakdown of vacuolar membranes minutes before malaria parasite egress from erythrocytes