Uric acid utilization by Mycobacterium intracellulare and Mycobacterium scrofulaceum isolates

Author:

Falkinham J O,George K L,Parker B C,Gruft H

Abstract

Forty-nine human and environmental isolates of Mycobacterium intracellulare and Mycobacterium scrofulaceum were tested for their ability to grow on uric acid and a number of its degradation products. Nearly all (88 to 90%) strains used uric acid or allantoin as a sole nitrogen source; fewer (47 to 69%) used allantoate, urea, or possibly ureidoglycollate. Enzymatic activities of one representative isolate demonstrated the existence of a uric acid degradation pathway resembling that in other aerobic microorganisms.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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