Rapid Microbiological Assay for Chlorhydroxyquinoline That Uses a Cryogenically Stored Inoculum

Author:

Cosgrove R. F.1

Affiliation:

1. International Development Laboratory, E. R. Squibb & Sons, Moreton, Wirral, Merseyside, L46 1QW, England

Abstract

A rapid microbiological assay for chlorhydroxyquinoline is described. It is a turbidimetric procedure that uses Streptococcus faecalis as the test organism. Results are available within 5 h. Data are presented to show the advantages of using a cryogenically stored inoculum over an inoculum prepared on a daily basis.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference14 articles.

1. Application of flow microcalorimetry to analytical problems: the preparation, storage and assay of frozen inocula ofSaccharomyces cerevisiae;Beezer A. E.;J. Appl. Bacteriol.,1976

2. The influence of chlorinated oxyquinoline derivatives on anaerobic micro-organisms;Ellenrieder V. M.;Arzneim. Forsch.,1972

3. Determination of chlorhydroxyquinoline in medicated pig feeds;Fairbrother J. E.;Analyst (London),1973

4. Antimycotic and antibacterial action of 8 quinolinols and nicotinic acid esters;Fiedler H.;Pharmazie,1966

5. Methods for the preservation of bacteria and fungi in liquid nitrogen;Froud D. J. R.;J. Sci. Technol. India,1972

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