A Novel Strain-Specific Neutralizing Epitope on Glycoprotein H of Human Cytomegalovirus-Reference-Cited by-同舟云学术

A Novel Strain-Specific Neutralizing Epitope on Glycoprotein H of Human Cytomegalovirus

Published:2021-08-25 Issue:18 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Thomas Marco¹^ORCID,Kropff Barbara¹,Schneider Andrea²,Winkler Thomas H.²,Görzer Irene³,Sticht Heinrich⁴,Britt William J.⁵,Mach Michael¹,Reuter Nina¹

Affiliation:

1. Virologisches Institut, Klinische und Molekulare Virologie, Friedrich Alexander Universität Erlangen-Nürnberg, Erlangen, Germany

2. Nikolaus-Fiebiger-Zentrum für Molekulare Medizin, Friedrich Alexander Universität Erlangen-Nürnberg, Erlangen, Germany

3. Center for Virology, Medical University of Vienna, Vienna, Austria

4. Institut für Biochemie, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany

5. Departments of Pediatrics, Microbiology and Neurobiology, Children’s Hospital of Alabama, University of Alabama, School of Medicine, Birmingham, Alabama, USA

Abstract

HCMV infections are life threatening to people with compromised or immature immune systems. Understanding the antiviral antibody repertoire induced during HCMV infection is a necessary prerequisite to define protective antibody responses.

Funder

Deutsche Forschungsgemeinschaft

HHS | NIH | OSC | Common Fund

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00657-21

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