Neutralization Epitopes in Trimer and Pentamer Complexes Recognized by Potent Cytomegalovirus-Neutralizing Human Monoclonal Antibodies-Reference-Cited by-同舟云学术

Neutralization Epitopes in Trimer and Pentamer Complexes Recognized by Potent Cytomegalovirus-Neutralizing Human Monoclonal Antibodies

Published:2022-12-21 Issue:6 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Ai Yuanbao¹²^ORCID,Wu Changwen¹³,Zhang Ming¹²,Jaijyan Dabbu Kumar⁴,Liu Tong¹³,Zan Lipeng¹²,Li Nan¹⁵,Yu Wei¹²,Wang Yueming¹³,Yuan Xiaohui¹³,Li Chengming¹³,Zheng Weihong³,Zhu Hua⁴,Liao Hua-Xin¹³²

Affiliation:

1. Department of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou, China

2. Institute of Biomedicine, Jinan University, Guangzhou, China

3. Trinomab Biotech Co., Ltd., Zhuhai, China

4. Department of Microbiology and Molecular Genetics, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA

5. Guangdong Provincial Key Laboratory of Bioengineering Medicine, Guangzhou, China

Abstract

The majority of the global population is infected with HCMV, but severe complications occur only in immunocompromised individuals. In addition, CMV infection is a major cause of birth defects in newborns.

Funder

Guangdong natural Science Foundation Project Fundamental and Applied Fundamental Research Fund

Zhuhai Innovative and Entrepreneurial Research Team Program

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01393-22

Reference66 articles.

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2. Who Is the Patient at Risk of CMV Recurrence: A Review of the Current Scientific Evidence with a Focus on Hematopoietic Cell Transplantation