Subversion of Lipopolysaccharide Signaling in Gingival Keratinocytes via MCPIP-1 Degradation as a Novel Pathogenic Strategy of Inflammophilic Pathobionts-Reference-Cited by-同舟云学术

Subversion of Lipopolysaccharide Signaling in Gingival Keratinocytes via MCPIP-1 Degradation as a Novel Pathogenic Strategy of Inflammophilic Pathobionts

Published:2021-06-29 Issue:3 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Gasiorek Anna¹,Dobosz Ewelina¹,Potempa Barbara²,Ciaston Izabela¹,Wilamowski Mateusz³,Oruba Zuzanna⁴,Lamont Richard J.²^ORCID,Jura Jolanta³,Potempa Jan¹²,Koziel Joanna¹^ORCID

Affiliation:

1. Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland

2. Department of Oral Immunity and Infectious Diseases, University of Louisville School of Dentistry, University of Louisville, Louisville, Kentucky, USA

3. Department of General Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland

4. Chair of Periodontology and Clinical Oral Pathology, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland

Abstract

Periodontitis is a highly prevalent disease caused by accumulation of a bacterial biofilm. Periodontal pathogens use a number of virulence strategies that are under intensive study to find optimal therapeutic approaches against bone loss.

Funder

National Science Center

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00502-21

Reference57 articles.

1. Risk factors for periodontitis;Van Dyke TE;J Int Acad Periodontol,2005

2. Microbial complexes in subgingival plaque