Selective imipenem resistance in Pseudomonas aeruginosa associated with diminished outer membrane permeability-Reference-Cited by-同舟云学术

Selective imipenem resistance in Pseudomonas aeruginosa associated with diminished outer membrane permeability

Published:1988-08 Issue:8 Volume:32 Page:1267-1268
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Studemeister A E¹,Quinn J P¹

Affiliation:

1. Department of Medicine, Loyola University Medical Center, Maywood, Illinois 60153.

Abstract

The permeability of the outer membranes of imipenem-susceptible and imipenem-resistant clinical isolates of Pseudomonas aeruginosa was investigated by the liposome swelling assay. Sugars and cephaloridine penetrated rapidly, whereas imipenem penetrated poorly into liposomes constructed from porin-rich outer membrane fractions of the resistant isolates.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.32.8.1267

Reference14 articles.

1. Imipenem: first of a new class of beta-lactam antibiotics;Barza M.;Ann. Intern. Med.,1985

2. Imipenem resistance in Pseudomonas aeruginosa resulting from diminished expression of an outer membrane protein;Buscher K.;Antimicrob. Agents Chemother.,1987

3. Penetration of P-lactams through Pseudomonas aeruginosa porin channels;Godfrey A. J.;Antimicrob. Agents Chemother.,1987

4. Role of porins in outer membrane permeability;Hancock R. E. W.;J. Bacteriol.,1987

5. Outer membrane of Pseudomonas aeruginosa: heat- and 2-mercaptoethanol-modifiable proteins;Hancock R. E. W.;J. Bacteriol.,1979

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