Impact of Na + -Translocating NADH:Quinone Oxidoreductase on Iron Uptake and nqrM Expression in Vibrio cholerae-Reference-Cited by-同舟云学术

Impact of Na + -Translocating NADH:Quinone Oxidoreductase on Iron Uptake and nqrM Expression in Vibrio cholerae

Published:2020-01-15 Issue:3 Volume:202 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Agarwal Shubhangi¹,Bernt Melanie¹,Toulouse Charlotte¹,Kurz Hannes²,Pfannstiel Jens³,D’Alvise Paul⁴,Hasselmann Martin⁴,Block Alisha M.⁵,Häse Claudia C.⁵,Fritz Günter¹,Steuber Julia¹

Affiliation:

1. Institute of Microbiology, University of Hohenheim, Stuttgart, Germany

2. Core Facility Hohenheim, Analytical Chemistry Core Facility, University of Hohenheim, Stuttgart, Germany

3. Core Facility Hohenheim, Mass Spectrometry Core Facility, University of Hohenheim, Stuttgart, Germany

4. Institute of Animal Science, University of Hohenheim, Stuttgart, Germany

5. Carlson College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA

Abstract

Investigating strategies of iron acquisition, storage, and delivery in Vibrio cholerae is a prerequisite to understand how this pathogen thrives in hostile, iron-limited environments such as the human host. In addition to highlighting the maturation of the respiratory complex NQR, this study points out the influence of NQR on iron metabolism, thereby making it a potential drug target for antibiotics.

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00681-19

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