Affiliation:
1. Department of Medical Microbiology and Hospital Hygiene, University Hospital, D-18057 Rostock
2. Institute of Medical Microbiology and Hygiene at the Helios Medical Center, D-99089 Erfurt, Germany
Abstract
ABSTRACT
We studied the specificity of the PLATELIA
CANDIDA
Ag enzyme immunoassay by using 130 isolates of 63 clinically relevant fungal species. Antigen extracts of seven
Candida
spp. (
Candida albicans
,
C. dubliniensis
,
C. famata
,
C. glabrata
,
C. guilliermondii
,
C. lusitaniae
, and
C. tropicalis
) repeatedly yielded positive reactions (>0.5 ng/ml).
Geotrichum candidum
and
Fusarium verticillioides
were found to yield borderline-positive reactions (0.25 to 0.50 ng/ml). Antigen preparations from the other 54 fungal species, including yeasts, molds, dermatophytes, and dimorphic fungi, did not cross-react in the assay.
Publisher
American Society for Microbiology
Reference13 articles.
1. Georges, E., M. L. Garrigues, D. Stynen, and J. L. Poirot. 1991. Spécificité in vitro d'un anticorps monoclonal (Acm) anti-mannane et du latex sensibilisé par cet anticorps au cours de la candidose disséminée expérimentale. J. Mycol. Med.118:21-24.
2. Jacquinot, P. M., Y. Plancke, B. Sendid, G. Strecker, and D. Poulain. 1998. Nature of Candida albicans-derived carbohydrate antigen recognized by a monoclonal antibody in patient sera and distribution over Candida species. FEMS Microbiol. Lett.169:131-138.
3. Kappe, R. 1989. Coexistence of free antigens, free antibodies and immune complexes in sera from patients with suspected deep-seated candidosis. Mycoses32:24-32.
4. Rapid clearance of Candida albicans mannan antigens by liver and spleen in contrast to prolonged circulation of Cryptococcus neoformans antigens
5. New cause for false-positive results with the Pastorex Aspergillus antigen latex agglutination test
Cited by
24 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献