Prediction of Human Pharmacokinetic Profiles of the Antituberculosis Drug Delamanid from Nonclinical Data: Potential Therapeutic Value against Extrapulmonary Tuberculosis-Reference-Cited by-同舟云学术

Prediction of Human Pharmacokinetic Profiles of the Antituberculosis Drug Delamanid from Nonclinical Data: Potential Therapeutic Value against Extrapulmonary Tuberculosis

Published:2021-07-16 Issue:8 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Shibata Masakazu¹^ORCID,Masuda Masatoshi²,Sasahara Katsunori¹,Sasabe Hiroyuki¹,Sasaki Tomohiro²,Kim Seongryul²,Takeuchi Kenji¹,Umehara Ken¹,Kashiyama Eiji¹

Affiliation:

1. Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

2. Headquarters of Clinical Development, Otsuka Pharmaceutical Co., Ltd., Osaka, Japan

Abstract

Delamanid has been studied extensively and approved for the treatment of pulmonary multidrug-resistant tuberculosis; however, its potential in the treatment of extrapulmonary tuberculosis remains unknown. We previously reported that, in rats, delamanid was broadly distributed to various tissues in addition to the lungs.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02571-20

Reference38 articles.

1. Synthesis and Antituberculosis Activity of a Novel Series of Optically Active 6-Nitro-2,3-dihydroimidazo[2,1-b]oxazoles

2. OPC-67683, a Nitro-Dihydro-Imidazooxazole Derivative with Promising Action against Tuberculosis In Vitro and In Mice

3. High proportion of extrapulmonary tuberculosis in a low prevalence setting: a retrospective cohort study

4. Diagnosis and Treatment of Extrapulmonary Tuberculosis

5. The effect of HIV infection on adult meningitis in Indonesia: a prospective cohort study

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