Copper Resistance in Enterococcus faecium , Mediated by the tcrB Gene, Is Selected by Supplementation of Pig Feed with Copper Sulfate-Reference-Cited by-同舟云学术

Copper Resistance in Enterococcus faecium , Mediated by the tcrB Gene, Is Selected by Supplementation of Pig Feed with Copper Sulfate

Published:2006-09 Issue:9 Volume:72 Page:5784-5789
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Hasman Henrik¹,Kempf Isabelle²,Chidaine Bérangère²,Cariolet Roland³,Ersbøll Annette Kjær⁴,Houe Hans⁴,Bruun Hansen Hans Christian⁴,Aarestrup Frank Møller¹

Affiliation:

1. Danish Institute for Food and Veterinary Research, Bülowsvej 27, 1790 Copenhagen V, Denmark

2. Unité de Mycoplasmologie-Bactériologie, Agence Française de Sécurité Sanitaire des Aliments, BP53, 22440 Ploufragan, France

3. Service de Production de Porcs Assainis et d'Expérimentation, Agence Française de Sécurité Sanitaire des Aliments, BP53, 22440 Ploufragan, France

4. The Royal Veterinary and Agricultural University, Grønnegårdsvej 8, 1870 Frederiksberg C, Denmark

Abstract

ABSTRACT The tcr gene cluster mediates in vitro copper resistance in Enterococcus faecium . Here we describe the selection of tcr -mediated copper resistance in E. faecium in an animal feeding experiment with young pigs fed 175 mg copper/kg feed (ppm), which is the concentration commonly used for piglets in European pig production. tcr -mediated copper resistance was not selected for in a control group fed low levels of copper (6 ppm). We also show coselection of macrolide- and glycopeptide-resistant E. faecium in the animal group fed the high level of copper. Finally, we identify the tcr genes in the enterococcal species E. mundtii , E. casseliflavus , and E. gallinarum for the first time.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.02979-05

Reference15 articles.

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