Extended-Spectrum β-Lactamases and Plasmid-Mediated AmpC Enzymes among Clinical Isolates of Escherichia coli and Klebsiella pneumoniae from Seven Medical Centers in Taiwan

Author:

Yan Jing-Jou1,Hsueh Po-Ren2,Lu Jang-Jih3,Chang Feng-Yee3,Shyr Jainn-Ming4,Wan Jen-Hsien5,Liu Yung-Ching5,Chuang Yin-Ching6,Yang Yi-Chueh6,Tsao Shih-Ming7,Wu Hsiu-Hung7,Wang Li-Shin8,Lin Tsuey-Pin9,Wu Hsiu-Mei1,Chen Hung-Mo1,Wu Jiunn-Jong1

Affiliation:

1. Departments of Pathology, Internal Medicine, and Medical Laboratory Science and Biotechnology, National Cheng Kung University College of Medicine

2. National Taiwan University Hospital

3. Triservice General Hospital, Taipei

4. Taichung Veterans General Hospital

5. China Medical College Hospital

6. Chi-Mei Medical Center

7. Chung Shan Medical University Hospital, Taichung

8. Buddhist Tzu-Chi General Hospital, Hualien, Taiwan

9. Department of Health and Nutrition, Chia Nan University of Pharmacy and Science, Tainan

Abstract

ABSTRACT Production of extended-spectrum β-lactamases and plasmid-mediated AmpC enzymes was investigated among 291 Escherichia coli and 282 Klebsiella pneumoniae isolates that showed decreased susceptibilities to extended-spectrum cephalosporins from seven Taiwanese medical centers. CTX-M-type and SHV-type enzymes were the most prevalent extended-spectrum β-lactamases. CMY-2-like and DHA-1-like β-lactamases were the most prevalent AmpC-type enzymes.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference20 articles.

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