Abstract
Five gentamicin-resistant clinical isolates of Staphylococcus aureus were found to contain self-transmissible plasmids of 32 to 37 megadaltons in size. Restriction endonuclease digests of the plasmids were markedly similar to those of reference plasmids of unrelated geographical origin, thus suggesting the significant contribution of common conjugal plasmids to the emergence of gentamicin resistance in S. aureus populations.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference11 articles.
1. Common R-plasmids in Staphylococcus aureus and Staphylococcus epidermidis during a nosocomial Staphylococcus aureus outbreak;Coben M. L.;Antimicrob. Agents Chemother.,1982
2. DavIks R. W. D. Botstein and J. R. Roth. 1980. A manual for genetic engineering: advanced bacterial genetics p. 123. Cold Spring Harbor Laboratory Cold Spring Harbor N.Y.
3. Transferability of macrolide, lincomycin, and streptogramin resistances between Group A, B, and D streptococci, Streptococcus pneumoniae, and Staphylococcus aureus;Engel H. W. B.;J. Bacteriol.,1980
4. Transfer of resistance plasmids from Staphylococcus epidermidis to Staphylococcus aureus: evidence for conjugative exchange of resistance;Forbes B. A.;J. Bacteriol.,1983
5. A rapid boiling method for the preparation of bacterial plasmids;Hohnes D. S.;Anal. Biochem.,1981
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