Advanced Molecular Detection of Malarone Resistance-Reference-Cited by-同舟云学术

Advanced Molecular Detection of Malarone Resistance

Published:2016-06 Issue:6 Volume:60 Page:3821-3823
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Talundzic Eldin¹²,Plucinski Mateusz M.¹³,Biliya Shweta⁴,Silva-Flannery Luciana M.¹²,Arguin Paul M.¹,Halsey Eric S.¹³,Barnwell John W.¹,Vannberg Fredrik⁴,Udhayakumar Venkatachalam¹

Affiliation:

1. Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

2. Atlanta Research and Education Foundation, Veterans Affairs Medical Center, Atlanta, Georgia, USA

3. President's Malaria Initiative, Atlanta, Georgia, USA

4. School of Biology, Georgia Institute of Technology, Atlanta, Georgia, USA

Abstract

ABSTRACT The rapid emergence of drug-resistant malaria parasites during the course of an infection remains a major challenge for providing accurate treatment guidelines. This is particularly important in cases of malaria treatment failure. Using a previously well-characterized case of malaria treatment failure, we show the utility of using next-generation sequencing for early detection of the rise and selection of a previously reported atovaquone-proguanil (malarone) drug resistance-associated mutation.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00171-16

Reference16 articles.

1. A mutation-specific PCR system to detect sequence variation in the dihydropteroate synthetase gene of Plasmodium falciparum

2. Rapid Real-Time PCR Genotyping of Mutations Associated with Sulfadoxine-Pyrimethamine Resistance in Plasmodium falciparum

3. Pyrosequencing, a High-Throughput Method for Detecting Single Nucleotide Polymorphisms in the Dihydrofolate Reductase and Dihydropteroate Synthetase Genes of Plasmodium falciparum

4. Tracking Origins and Spread of Sulfadoxine-ResistantPlasmodium falciparum dhpsAlleles in Thailand

5. Comparison of Sanger Sequencing, Pyrosequencing, and Melting Curve Analysis for the Detection of KRAS Mutations

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Unlocking the microbial studies through computational approaches: how far have we reached?;Environmental Science and Pollution Research;2023-03-15

2. Comparative analysis of targeted next-generation sequencing for Plasmodium falciparum drug resistance markers;Scientific Reports;2022-04-01

3. Molecular surveillance of drug resistance: Plasmodium falciparum artemisinin resistance single nucleotide polymorphisms in Kelch protein propeller (K13) domain from Southern Pakistan;Malaria Journal;2021-04-07

4. Machine learning and applications in microbiology;FEMS Microbiology Reviews;2021-03-16

5. Selection of Cytochrome b Mutants Is Rare among Plasmodium falciparum Patients Failing Treatment with Atovaquone-Proguanil in Cambodia;Antimicrobial Agents and Chemotherapy;2021-02-17