Affiliation:
1. Department of Food Science, University of Illinois, Urbana, Illinois
Abstract
The growth of
Staphylococcus aureus
MF 31 was suppressed when grown in association with
Streptococcus diacetilactis
and other lactic streptococci. The data indicated that the initial proportion of staphylococci present in the medium was of less importance than the depletion of vital nutrients. Investigation revealed that factors present in Yeast Nitrogen Base medium could reverse the inhibition which was due to antagonism. The major factor found was nicotinamide, and further study revealed that the biological availability of this compound was influenced by the
p
H of the medium. The addition of nicotinamide to depleted media with careful control of the
p
H resulted in increased growth of
S. aureus
in the test system. Further data indicated that additional factors may affect the degree of growth by
S. aureus
in depleted media.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
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