Antibodies Specific to Membrane Proteins Are Effective in Complement-Mediated Killing of Mycoplasma bovis-Reference-Cited by-同舟云学术

Antibodies Specific to Membrane Proteins Are Effective in Complement-Mediated Killing of Mycoplasma bovis

Published:2019-12 Issue:12 Volume:87 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Zhang Yun-ke¹,Li Xia¹,Zhao Hao-ran¹,Jiang Fei²,Wang Zhan-hui¹,Wu Wen-xue¹

Affiliation:

1. Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing, China

2. China Animal Disease Control Center, Beijing, China

Abstract

The metabolic inhibition (MI) test is a classic test for the identification of mycoplasmas, used for measuring the growth-inhibiting antibodies directed against acid-producing mycoplasmas, although their mechanism still remains obscure. To determine the major antigens involved in the immune killing of Mycoplasma bovis , we used a pulldown assay with anti- M. bovis antibodies as bait and identified nine major antigens.

Funder

Agriculture Research System of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00740-19

Reference41 articles.

1. Molecular Biology and Pathogenicity of Mycoplasmas

2. Mycoplasmas and their host: emerging and re-emerging minimal pathogens

3. Virulence, persistence and dissemination of Mycoplasma bovis