Genetic suppression meets structure prediction: probing a spore germination receptor complex-Reference-Cited by-同舟云学术

Genetic suppression meets structure prediction: probing a spore germination receptor complex

Published:2021-12-06 Issue: Volume: Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Moir Anne¹,Popham David²^ORCID

Affiliation:

1. School of Biosciences, University of Sheffield, Western Bank, Sheffield S10 2TN, UK

2. Dept of Biological Sciences, Virginia Tech, Blacksburg, VA 24061, USA

Abstract

Despite the thousands of spore germinant receptor operons identified in genomes of Bacilli and Clostridia, understanding how the three essential receptor components act as a signal transduction machine in germination remains limited. The paper by Amon et al in this issue uses the classical genetic approach of suppression to define a region of likely interaction between the GerAA and GerAB proteins: it provides a first glimpse into potential events within the receptor complex.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00579-21

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