Time-Kill Studies of the Antianaerobe Activity of Garenoxacin Compared with Those of Nine Other Agents-Reference-Cited by-同舟云学术

Time-Kill Studies of the Antianaerobe Activity of Garenoxacin Compared with Those of Nine Other Agents

Published:2003-04 Issue:4 Volume:47 Page:1399-1402
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Credito Kim L.¹,Jacobs Michael R.²,Appelbaum Peter C.¹

Affiliation:

1. Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania 17033

2. Case Western Reserve University, Cleveland, Ohio 44106

Abstract

ABSTRACT The activities of garenoxacin, ciprofloxacin, levofloxacin, moxifloxacin, trovafloxacin, amoxicillin-clavulanate, piperacillin-tazobactam, imipenem, clindamycin, and metronidazole against 20 anaerobes were tested. At two times the MIC, garenoxacin was bactericidal against 19 of 20 strains after 48 h and against 17 of 20 after 24 h. Other drugs, except clindamycin (which gave lower killing rates), gave killing rates similar to those for garenoxacin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.47.4.1399-1402.2003

Reference19 articles.

1. Appelbaum, P. C. 1995. Quinolone activity against anaerobes: microbiological aspects. Drugs49(Suppl. 2):76-80.

2. Beta-lactamase production and susceptibilities to amoxicillin, amoxicillin-clavulanate, ticarcillin, ticarcillin-clavulanate, cefoxitin, imipenem, and metronidazole of 320 non-Bacteroides fragilis Bacteroides isolates and 129 fusobacteria from 28 U.S. centers

3. Susceptibilities of 394 Bacteroides fragilis, non-B. fragilis group Bacteroides species, and Fusobacterium species to newer antimicrobial agents

4. Appelbaum, P. C., S. K. Spangler, and M. R. Jacobs. 1993. Susceptibility of 539 gram-positive and gram-negative anaerobes to new agents, including RP 59500, biapenem, trospectomycin and piperacillin/tazobactam. J. Antimicrob. Chemother.32:223-231.

5. Antimicrobial Activities of BMS-284756 Compared with Those of Fluoroquinolones and β-Lactams against Gram-Positive Clinical Isolates

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