Development and Application of a Core Genome Multilocus Sequence Typing Scheme for the Health Care-Associated Pathogen Pseudomonas aeruginosa

Author:

Stanton Richard A.1,McAllister Gillian1,Daniels Jonathan B.1,Breaker Erin1,Vlachos Nicholas1,Gable Paige1,Moulton-Meissner Heather1,Halpin Alison Laufer12

Affiliation:

1. Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

2. Commissioned Corps, U.S. Public Health Service, Rockville, Maryland, USA

Abstract

Pseudomonas aeruginosa is an opportunistic human pathogen that frequently causes health care-associated infections (HAIs). Due to its metabolic diversity and ability to form biofilms, this Gram-negative nonfermenting bacterium can persist in the health care environment, which can lead to prolonged HAI outbreaks. We describe the creation of a core genome multilocus sequence typing (cgMLST) scheme to provide a stable platform for the rapid comparison of P. aeruginosa isolates using whole-genome sequencing (WGS) data.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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