In vitro and in vivo activities of sparfloxacin, other quinolones, and tetracyclines against Chlamydia trachomatis

Author:

Nakata K1,Maeda H1,Fujii A1,Arakawa S1,Umezu K1,Kamidono S1

Affiliation:

1. Department of Urology, School of Medicine, Kobe University, Japan.

Abstract

Sparfloxacin was more potent than other quinolones (tosufloxacin, lomefloxacin, ciprofloxacin, ofloxacin, fleroxacin, enoxacin, and norfloxacin) and as potent as minocycline and doxycycline in activity against Chlamydia trachomatis in vitro and in vivo. Sparfloxacin was more bactericidal than minocycline against C. trachomatis D/UW-3/Cx.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference19 articles.

1. Activity of new quinolone derivatives against gential pathogens;Azmar M. J.;Antimicrob. Agents Chemother.,1985

2. Ofloxacin: therapeutic results in Chlamydia trachomatis urethritis;Biscoff W.;Infection,1986

3. Ignatius W. F. W. Linton M. Simbul R. Thorup B. Mclanghlin V. Rohm and P. A. Quinn. 1987. Treatment of nongonococcal urethritis with ciprofloxacin. Am. J. Med. 82(Suppl. 4A):311-316.

4. Kanamaru M. M. Nakashima T. Uematsu and Y. Takikuchi. 1988. Program Abstr. 28th Intersci. Conf. Antimicrob. Agents Chemother abstr. 1490.

5. A prospective single-blind trial of minocycline and doxycycline in the treatment of genital Chlamydia trachomatis infection in women;Kovacs G. T.;Med. J. Aust.,1989

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