Activities of new quinoline derivatives against genital pathogens

Author:

Aznar J,Caballero M C,Lozano M C,de Miguel C,Palomares J C,Perea E J

Abstract

The in vitro activities of four quinoline carboxylic acids against 48 strains of Neisseria gonorrhoeae, 10 of Chlamydia trachomatis, and 32 of Ureaplasma urealyticum were compared. Ciprofloxacin was the most active against N. gonorrhoeae and C. trachomatis but had poor bactericidal activity against U. urealyticum, whereas ofloxacin showed the most bactericidal activity against U. urealyticum but was less active than ciprofloxacin against the two former pathogens. Norfloxacin and enoxacin were less active against all the studied pathogens.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference23 articles.

1. Genital mycoplasmas in patients with non-gonococcal non-chlamydial urethritis (NGCU) and in healthy volunteers;Alvarez-Dardet C.;Eur. J. Sex. Trans. Dis.,1982

2. Etiology of NGU: evidence for Chlamydia trachomatis and Ureaplasma urealyticum;Bowie W. R.;J. Clin. Invest.,1977

3. Mucopurulent cervicitis-the ignored counterpart in women of urethritis in men;Brunham R. C.;N. Engl. J. Med.,1984

4. In vitro activity of enoxacin, a quinoline carboxylic acid, compared with those of norfloxacin, new P-lactams, aminoglycosides, and trimethoprim;Chin N.;Antimicrob. Agents Chemother.,1983

5. Pharmacokinetics and tissue concentration of ciprofloxacin;Crump B.;Antimicrob. Agents Chemother.,1983

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