Antioxidant function of fungal melanin-Reference-Cited by-同舟云学术

Antioxidant function of fungal melanin

Published:1993-11 Issue:21 Volume:175 Page:7102-7104
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Jacobson E S¹,Tinnell S B¹

Affiliation:

1. Research Service, McGuire Veterans Affairs Medical Center, Richmond, Virginia 23249.

Abstract

Polyphenols have been implicated in the virulence and oxidant resistance of Cryptococcus neoformans. Although monomeric polyphenols did not protect against the prooxidant, plumbagin, polymeric dopamine-melanin conferred resistance both to hypochlorite and to permanganate. The physiologic antioxidant capacity conferred by melanin was found to be 21.3 x 10(-15) mole-equivalents per cell, a value which approximates oxidant production by stimulated macrophages.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.175.21.7102-7104.1993

Reference19 articles.

1. Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent;Babior B. M.;J. Clin. Invest.,1973

2. Cohen G. and R. E. Heikkila. 1977. In vivo scavenging of superoxide radicals by catecholamines p. 351-365. In A. M. Michelson J. M. McCord and I. Fridovich (ed.) Superoxide and superoxide dismutases. Academic Press Inc. New York.

3. Pathogenicity and virulence of wild-type and melanin-deficient Wangiella dermatitidis;Dixon D. M.;J. Med. Vet. Mycol.,1987

4. Hydrogen peroxide release by alveolar macrophages from sarcoid patients and by alveolar macrophages from normals after exposure to recombinant interferons alpha A, beta and gamma and 1,25- dihydroxyvitamin D3;Fels A.;J. Clin. Invest.,1987

5. Electron transfer properties of melanin;Gan E. V.;Arch. Biochem. Biophys.,1976

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