Molecular Impact of the M184V Mutation in Human Immunodeficiency Virus Type 1 Reverse Transcriptase
Author:
Affiliation:
1. McGill AIDS Centre, Lady Davis Institute-Jewish General Hospital
2. Department of Microbiology and Immunology
3. Experimental Medicine, McGill University, Montreal, Québec H3T 1E2, Canada
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Link
https://journals.asm.org/doi/pdf/10.1128/AAC.47.11.3377-3383.2003
Reference72 articles.
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2. Arion, D., N. Kaushik, S. McCormick, G. Borkow, and M. A. Pamiak. 1998. HIV-1 resistance to 3′-azido,3′-deoxythymidine (AZT): increased DNA polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase. Biochemistry37:15908-15917.
3. Back, N. K. T., M. Nijhuis, W. Keulen, C. A. B. Boucher, B. B. O. Essnik, A. B. P. van Kuilenburg, A. H. van Gennip, and B. Berkhout. 1996. Reduced replication of 3TC-resistant HIV-l variants in primary cells due to a processivity defect of the reverse transcriptase enzyme. EMBO J.15:4040-4049.
4. Bebenek K. and T. A. Kunkel. 1993. The fidelity of retroviral reverse transcriptases p. 85-102. In A. M. Skalka and S. P. Goff (ed.) Reverse transcriptase. Cold Spring Harbor Laboratory Press Cold Spring Harbor Laboratory N.Y.
5. Bebenek, K., W. A. Beard, T. A. Darden, L. Li, R. Prasad, B. A. Luton, D. G. Gorenstein, S. H. Wilson, and T. A. Kunkel. 1998. A minor groove binding track in reverse transcriptase. Nat. Struct. Biol.4:194-197.
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