Antimicrobial Resistance of Neisseria gonorrhoeae Isolates from High-Risk Men in Johannesburg, South Africa

Author:

Maduna Liteboho D.1,Kock Marleen M.12,van der Veer Brian M. J. W.3ORCID,Radebe Oscar45,McIntyre James4,van Alphen Lieke B.3,Peters Remco P. H.1346ORCID

Affiliation:

1. Department of Medical Microbiology, University of Pretoria, Pretoria, South Africa

2. Tshwane Academic Division, National Health Laboratory Service, Pretoria, South Africa

3. Department of Medical Microbiology, School of Public Health and Primary Care (CAPHRI), Maastricht University Medical Centre, Maastricht, The Netherlands

4. Anova Health Institute, Johannesburg, South Africa

5. EpiC Family Health International (FHI360), Pretoria, South Africa

6. Foundation for Professional Development, Research Unit, East London, South Africa

Abstract

Neisseria gonorrhoeae antimicrobial drug resistance has emerged worldwide; however, the situation in sub-Saharan Africa is not well documented. We investigated the molecular epidemiology and occurrence of antimicrobial resistance in Neisseria gonorrhoeae infections in two core transmission groups of men in Johannesburg, South Africa. We recruited men who have sex with men (MSM) presenting with urethral discharge and men with recurrent episodes of urethral discharge.

Funder

National Health Laboratory Service Research Trust

University of Pretoria Postgraduate Study Abroad Programme

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference52 articles.

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3. Tacconelli E Magrini N Kahlmeter G Singh N. 2017. Global priority list of antibiotic-resistant bacteria to guide research discovery and development of new antibiotics. World Health Organization Geneva Switzerland. https://www.who.int/medicines/publications/global-priority-list-antibiotic-resistant-bacteria/en/.

4. Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future

5. Genetic relatedness of ceftriaxone-resistant and high-level azithromycin resistant Neisseria gonorrhoeae cases, United Kingdom and Australia, February to April 2018

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