Antibiotic Susceptibilities of Group C and Group G Streptococci Isolated from Patients with Invasive Infections: Evidence of Vancomycin Tolerance among Group G Serotypes-Reference-Cited by-同舟云学术

Antibiotic Susceptibilities of Group C and Group G Streptococci Isolated from Patients with Invasive Infections: Evidence of Vancomycin Tolerance among Group G Serotypes

Published:1999-10 Issue:10 Volume:37 Page:3380-3383
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Zaoutis Theoklis¹²,Schneider Barbara³,Steele Moore Lynn³,Klein Joel D.¹²

Affiliation:

1. Division of Pediatric Infectious Diseases, Alfred I. duPont Hospital for Children,1 and

2. Jefferson Medical College, Philadelphia, Pennsylvania2

3. Infectious Diseases Laboratory, Christiana Care Health System,3 Wilmington, Delaware, and

Abstract

ABSTRACT A retrospective review of medical records for 32 patients with invasive group C streptococcus (GCS) or group G streptococcus (GGS) infections was performed. MICs and minimum bactericidal concentrations (MBCs) of penicillin, erythromycin, and vancomycin for all isolates were obtained. Tolerance of vancomycin, defined as an MBC 32 or more times higher than the MIC, was exhibited by 18 GGS isolates (54%). The identification of tolerance in clinical isolates of GGS and GCS may have clinical implications in treating these seriously ill patients.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.37.10.3380-3383.1999

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