Tiny Earth: A Big Idea for STEM Education and Antibiotic Discovery

Author:

Hurley Amanda1,Chevrette Marc G.1ORCID,Acharya Deepa D.1,Lozano Gabriel L.12,Garavito Manuel1,Heinritz Jen1,Balderrama Luis13,Beebe Mara1,DenHartog Martel L.1,Corinaldi Kamiyah45,Engels Renee1,Gutierrez Alyssa46,Jona Orli1,Putnam Josephine H. I.1,Rhodes Brody47,Tsang Tiffany8,Hernandez Simon9,Bascom-Slack Carol10,Blum Jessamina E.11,Price Paul A.12,Davis Debra13,Klein Joanna14,Pultorak Joshua1,Sullivan Nora L.15,Mouncey Nigel J.16,Dorrestein Pieter C.17,Miller Sarah4,Broderick Nichole A.1819ORCID,Handelsman Jo1ORCID

Affiliation:

1. Wisconsin Institute for Discovery and Department of Plant Pathology, University of Wisconsin-Madison, Madison, Wisconsin, USA

2. Division of Infectious Diseases and Division of Gastroenterology, Department of Pediatrics, Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts, USA

3. Hamline University, Minneapolis, Minnesota, USA

4. Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, Wisconsin, USA

5. Colorado State University, Fort Collins, Colorado, USA

6. University of Alabama, Tuscaloosa, Alabama, USA

7. University of West Alabama, Livingston, Alabama, USA

8. Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, USA

9. University of Rochester Medical Center, Rochester, New York, USA

10. Department of Medical Education, Tufts University, Boston, Massachusetts, USA

11. University of Minnesota Medical School, Minneapolis, Minnesota, USA

12. Department of Biology, Eastern Michigan University, Ypsilanti, Michigan, USA

13. Department of Biology, Wingate University, Wingate, North Carolina, USA

14. Department of Biology and Biochemistry, University of Northwestern-St. Paul, Saint Paul, Minnesota, USA

15. Biology Department, Citrus College, Glendora, California, USA

16. Joint Genome Institute, Berkeley, California, USA

17. Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA

18. Department of Molecular and Cell Biology, University of Connecticut, Mansfield, Connecticut, USA

19. Department of Biology, Johns Hopkins University, Baltimore, Maryland, USA

Abstract

The world faces two seemingly unrelated challenges—a shortfall in the STEM workforce and increasing antibiotic resistance among bacterial pathogens. We address these two challenges with Tiny Earth, an undergraduate research course that excites students about science and creates a pipeline for antibiotic discovery.

Funder

HHS | National Institutes of Health

Howard Hughes Medical Institute

Wisconsin Alumni Research Foundation

UW | Institute for Clinical and Translational Research, University of Wisconsin, Madison

Leona M. and Harry B. Helmsley Charitable Trust

Alfred P. Sloan Foundation

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Reference37 articles.

1. National Academies of Science, Engineering, and Medicine. 2016. Barriers and opportunities for 2-year and 4-year STEM degrees: systemic change to support students’ diverse pathways. Malcolm S, Feder M (ed), National Academies Press, Washington, DC.

2. President’s Council of Advisors on Science and Technology. 2012. Report to the president engage to excel: producing one million additional college graduates with degrees in science technology engineering and mathematics. https://aaas-arise.org/resource/engage-to-excel-producing-one-million-additional-college-graduates-with-degrees-in-science-technology-engineering-and-mathematics/.

3. Talking about Leaving Revisited

4. Active learning narrows achievement gaps for underrepresented students in undergraduate science, technology, engineering, and math

5. Scientific Teaching in Practice

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