Intracellular Staphylococcus aureus Perturbs the Host Cell Ca 2+ Homeostasis To Promote Cell Death-Reference-Cited by-同舟云学术

Intracellular Staphylococcus aureus Perturbs the Host Cell Ca 2+ Homeostasis To Promote Cell Death

Published:2020-12-22 Issue:6 Volume:11 Page:
ISSN:2161-2129
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Stelzner Kathrin¹,Winkler Ann-Cathrin¹,Liang Chunguang²,Boyny Aziza¹,Ade Carsten P.³,Dandekar Thomas²,Fraunholz Martin J.¹^ORCID,Rudel Thomas¹⁴^ORCID

Affiliation:

1. Chair of Microbiology, University of Würzburg, Würzburg, Germany

2. Chair of Bioinformatics, University of Würzburg, Würzburg, Germany

3. Chair of Biochemistry and Molecular Biology, University of Würzburg, Würzburg, Germany

4. Helmholtz Institute for RNA-based Infection Research (HIRI), Würzburg, Germany

Abstract

Despite being regarded as an extracellular bacterium, the pathogen Staphylococcus aureus can invade and survive within human cells. The intracellular niche is considered a hideout from the host immune system and antibiotic treatment and allows bacterial proliferation.

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.02250-20

Reference103 articles.

1. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks

2. Nasal Carriage as a Source ofStaphylococcus aureusBacteremia

3. Staphylococcus aureusInfections