Molecular Mechanism of Antagonism between the Y181C and E138K Mutations in HIV-1 Reverse Transcriptase-Reference-Cited by-同舟云学术

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Molecular Mechanism of Antagonism between the Y181C and E138K Mutations in HIV-1 Reverse Transcriptase

Published:2012-09-19 Issue:23 Volume:86 Page:12983-12990
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:Journal of Virology

Author:

Xu H.-T.,Oliveira M.,Asahchop E. L.,McCallum M.,Quashie P. K.,Han Y.,Quan Y.,Wainberg M. A.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference50 articles.

1. Docking analysis and resistance evaluation of clinically relevant mutations associated with the HIV-1 non-nucleoside reverse transcriptase inhibitors nevirapine, efavirenz and etravirine;Alcaro;ChemMedChem,2011

2. The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs;Ambrose;J. Virol.,2009

3. Mutants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors demonstrate altered rates of RNase H cleavage that correlate with HIV-1 replication fitness in cell culture;Archer;J. Virol.,2000

4. Comparison of deoxyoligonucleotide and tRNA(Lys-3) as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/template-switching reaction;Arts;J. Biol. Chem.,1994

5. Characterization of the E138K resistance mutation in HIV-1 reverse transcriptase conferring susceptibility to etravirine in B and non-B HIV-1 subtypes;Asahchop;Antimicrob. Agents Chemother.,2011

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1. Escaping from Flatland: Multiparameter Optimization Leads to the Discovery of Novel Tetrahydropyrido[4,3-d]pyrimidine Derivatives as Human Immunodeficiency Virus-1 Non-nucleoside Reverse Transcriptase Inhibitors with Superior Antiviral Activities against Non-nucleoside Reverse Transcriptase Inhibitor-Resistant Variants and Favorable Drug-like Profiles;Journal of Medicinal Chemistry;2023-05-31

2. Artificial intelligence in drug combination therapy;Briefings in Bioinformatics;2018-02-09

3. M184I/V substitutions and E138K/M184I/V double substitutions in HIV reverse transcriptase do not significantly affect the antiviral activity of EFdA;Journal of Antimicrobial Chemotherapy;2017-08-22

4. HIV-1 capsid uncoating initiates after the first strand transfer of reverse transcription;Retrovirology;2016-08-22

5. Drug susceptibility to etravirine and darunavir among Human Immunodeficiency Virus Type 1-derived pseudoviruses in treatment-experienced patients with HIV/AIDS in South Korea;Virology Journal;2015-04-09

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