Detection of mcr-1 Gene among Escherichia coli Isolates from Farmed Fish and Characterization of mcr-1 -Bearing IncP Plasmids

Author:

Lv Luchao1,Cao Yuping1,Yu Peixin1,Huang Raorao1,Wang Jing1,Wen Qiaoling1,Zhi Chanping1,Zhang Qianhui1,Liu Jian-Hua1

Affiliation:

1. College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong, China

Abstract

ABSTRACT The presence of the mcr-1 gene in Escherichia coli isolated from retail freshwater fish was investigated. Seven (3.65%) clonally unrelated original E. coli isolates from grass carp were positive for mcr-1 . The mcr-1 genes were encoded by either chromosomes ( n = 2) or conjugative plasmids (2 IncI2, 2 IncP, and 1 IncX4). The IncP plasmids were similar to other mcr-1 -harboring IncP plasmids from China, though the insertion sites varied. Our report warrants further surveillance of resistance genes in aquaculture.

Funder

National Training Program of Innovation and Entrepreneurship for Undergraduates

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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