Greater Invasion and Persistence of <i>mcr-1-</i> Bearing Plasmids in Escherichia coli than in Klebsiella pneumoniae-Reference-Cited by-同舟云学术

Greater Invasion and Persistence of mcr-1- Bearing Plasmids in Escherichia coli than in Klebsiella pneumoniae

Published:2023-04-13 Issue:2 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Liu Yi-Yun¹²,Zhu Xiao-Qing¹,Nang Sue C.³⁴,Xun Haoliang¹,Lv Luchao¹²,Yang Jun¹²,Liu Jian-Hua¹²^ORCID

Affiliation:

1. National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, China

2. Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China

3. Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia

4. Department of Microbiology, School of Biomedical Sciences, Monash University, Clayton, Victoria, Australia

Abstract

As infections caused by multidrug-resistant “superbugs” are increasing globally, polymyxins are often the only viable therapeutic option. Alarmingly, the wide spread of the plasmid-mediated polymyxin resistance gene mcr-1 is restricting the clinical utility of this last-line treatment option.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.03223-22

Reference36 articles.

1. The negative impact of antibiotic resistance

2. Risk stratification and treatment of ICU-acquired pneumonia caused by multidrug- resistant/extensively drug-resistant/pandrug-resistant bacteria

3. A Comparison of the Mortality Risk Associated With Ventilator-Acquired Bacterial Pneumonia and Nonventilator ICU-Acquired Bacterial Pneumonia*

4. World Health Organization. 2017. Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics. World Health Organization, Geneva, Switzerland.

5. Colistin: The Revival of Polymyxins for the Management of Multidrug-Resistant Gram-Negative Bacterial Infections

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A multi-channel electrochemical biosensor based on polyadenine tetrahedra for the detection of multiple drug resistance genes;The Analyst;2024

2. Promising treatments for refractory pneumonia caused by multidrug-resistant Klebsiella pneumoniae;Journal of Drug Delivery Science and Technology;2023-09