Neoplastic transformation by E26 leukemia virus is mediated by a single protein containing domains of gag and myb genes-Reference-Cited by-同舟云学术

Neoplastic transformation by E26 leukemia virus is mediated by a single protein containing domains of gag and myb genes

Published:1984-04 Issue:1 Volume:50 Page:280-283
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Klempnauer K H,Bishop J M

Abstract

The genome of avian leukemia virus E26 shares homology with v-myb, the oncogene of avian myeloblastosis virus, and encodes a protein with an Mr of 135,000. Analyses of tryptic oligopeptides show that this protein is related to the proteins encoded by gag (Pr76gag) as well as v-myb (p45v-myb[AMV] ) and c-myb (p75c-myb). We found no evidence for the existence of additional myb-related proteins or subgenomic species of myb-related RNA in myeloblasts transformed by strain E26.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.50.1.280-283.1984

Reference21 articles.

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