Rapid Detection of the Pandemic Methicillin-Resistant Staphylococcus aureus Clone ST 239, a Dominant Strain in Asian Hospitals

Author:

Feil Edward J.1,Nickerson Emma K.23,Chantratita Narisara2,Wuthiekanun Vanaporn2,Srisomang Pramot4,Cousins Richard1,Pan WuBin5,Zhang Ge5,Xu BangLao56,Day Nicholas P. J.23,Peacock Sharon J.23

Affiliation:

1. Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom

2. Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand

3. Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, United Kingdom

4. Sappasithiprasong Hospital, Ubon Ratchathani 34000, Thailand

5. School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510080, People's Republic of China

6. Clinical Microbiology Laboratory, Guangzhou First Municipal People's Hospital, Guangzhou 510080, People's Republic of China

Abstract

ABSTRACT We describe and validate a novel PCR assay to detect the pandemic hospital-acquired methicillin-resistant Staphylococcus aureus (HA-MRSA) lineage ST 239. Results based on previously uncharacterized isolates from a hospital in northeast Thailand support the view that at least 90% of HA-MRSA isolates in mainland Asia correspond to ST 239 or close relatives.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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