Escherichia coli with a Self-Transferable, Multiresistant Plasmid Coding for Metallo-β-Lactamase VIM-1

Author:

Miriagou Vivi1,Tzelepi Eva1,Gianneli Dimitra2,Tzouvelekis Leonidas S.3

Affiliation:

1. Laboratory of Bacteriology, Hellenic Pasteur Institute

2. Laboratory of Microbiology, “Tzanion” General Hospital, Piraeus, Greece

3. Department of Microbiology, Medical School, University of Athens, Athens

Abstract

ABSTRACT An Escherichia coli strain exhibiting decreased susceptibility to carbapenems was isolated from a hospitalized patient in Greece. The strain carried a self-transferable plasmid coding for metallo-β-lactamase VIM-1. bla VIM-1 , along with aacA7 , dhfrI , and aadA , was included as a gene cassette in a novel class 1 integron. A Citrobacter freundii ampC -derived gene, not associated with the integron, was also located in the same plasmid.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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