Low Relative Abundances of the Mucolytic Bacterium Akkermansia muciniphila and Bifidobacterium spp. in Feces of Children with Autism-Reference-Cited by-同舟云学术

Low Relative Abundances of the Mucolytic Bacterium Akkermansia muciniphila and Bifidobacterium spp. in Feces of Children with Autism

Published:2011-09-15 Issue:18 Volume:77 Page:6718-6721
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Wang Lv¹,Christophersen Claus T.²,Sorich Michael J.¹,Gerber Jacobus P.¹,Angley Manya T.¹,Conlon Michael A.²

Affiliation:

1. Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia 5001, Australia

2. Preventative Health National Research Flagship, CSIRO Food and Nutritional Sciences, Adelaide, South Australia 5001, Australia

Abstract

ABSTRACT Gastrointestinal disturbance is frequently reported for individuals with autism. We used quantitative real-time PCR analysis to quantify fecal bacteria that could influence gastrointestinal health in children with and without autism. Lower relative abundances of Bifidobacteria species and the mucolytic bacterium Akkermansia muciniphila were found in children with autism, the latter suggesting mucus barrier changes.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.05212-11

Reference29 articles.

1. Gastrointestinal flora and gastrointestinal status in children with autism – comparisons to typical children and correlation with autism severity

2. Urinary p-cresol is elevated in small children with severe autism spectrum disorder;Altieri L.;Biomarkers,2011

3. American Psychiatric Association. 2000. Diagnostic and statistical manual of mental disorders 4th ed. American Psychiatric Press Washington DC.

4. Intestinal Integrity and Akkermansia muciniphila , a Mucin-Degrading Member of the Intestinal Microbiota Present in Infants, Adults, and the Elderly

5. Intestinal mucus barrier in normal and inflamed colon;Corazziari E. S.;J. Pediatr. Gastroenterol. Nutr.,2009

Cited by 346 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The biofunction of Akkermansia muciniphila in intestinal-related diseases;Microbiome Research Reports;2024-09-05

2. Atypical Gut Microbiota Composition in a Mouse Model of Developmental Stuttering;2024-09-03

3. Efficacy and safety of Bacteroides fragilis BF839 for pediatric autism spectrum disorder: a randomized clinical trial;Frontiers in Nutrition;2024-09-03

4. The complex interplay between autism spectrum disorder and gut microbiota in children: A comprehensive review;Behavioural Brain Research;2024-09

5. Akkermansia muciniphila : A promising probiotic against inflammation and metabolic disorders;Virulence;2024-08-27